Skip to content

3 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Sep 2026

Novel mTORC1 Booster LAPTM4A Potentiates Pathological Cardiac Hypertrophy.

BACKGROUND Excessive unnecessary protein accumulation in cardiomyocyte is a leading contributor for pathological cardiac hypertrophy and has been found closely regulated by the mTORC1 (mechanistic target of rapamycin complex 1) signaling and lysosome transmembrane proteins. However, the precise regulatory mechanism str...

Yu-Feng Hu, Wei Li, Man-Li Hu et al. · 0 citations
Aug 2026

Facilitation of Autophagosome-Lysosome Fusion by LAPTM4A: A Novel Strategy for Attenuating Myocardial Ischemia-Reperfusion Injury.

BACKGROUND Myocardial ischemia-reperfusion (MIR) injury compromises therapeutic effects of revascularization and leads to functional impairment and exacerbation of structural damage in the heart. Limiting the damage caused by MIR is crucial but is still an unmet clinical need because of the complexity of the underlying...

Si-Yi Zhou, Jia-Yi Liu, Man-Li Hu et al. · 0 citations
Review Jul 2026

Mitophagy in Cardiovascular Disease: From Mechanistic Insights to Therapeutic Horizons.

Cardiovascular diseases (CVDs) remain a leading cause of death worldwide, with a complex and multifactorial pathophysiology. Given its high energy demands, the heart is critically dependent on mitochondrial energy production and metabolic homeostasis. Mitophagy, a selective form of autophagy, represents a crucial intra...

Deyi Guo, Kun Wang, Jingwen Zhang et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.