Topology-Programmed Peptide Architectures Orchestrate Durable Tumor Targeting and Cascade Antitumor Immunity
Peptide supramolecular systems offer recognition and biocompatibility for precision theranostics, yet their in vivo performance is limited by insufficient structural stability, poor retention, and loss of accessible recognition interfaces under physiological perturbations. Herein, a topology-programmed supramolecular...