Open access
Oct 2026
Sestrin1 Ameliorates Senescence and Mediates the Protective Effects of Exercise Against Hepatic Abnormality in C57BL/6J Mice.
It is identified that the Sestrin1/Drp1/cGAS-STING axis plays a pivotal role in liver aging and positioned Sestrin1 as a vital therapeutic target, serving as a key mediator of the anti-aging benefits of exercise training.
Xue-Ge Yang, Yu-Chen Zou, Xiu-Ru Li et al.
· Journal of Cellular Physiolo... · 0 citations