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Yu Chen

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Review Open access 2026

Growth differentiation factor-15 in diabetic kidney disease: From pathophysiological mechanisms to clinical applications

Clinically, circulating and urinary GDF15 levels correlate with disease severity and independently predict renal function decline, suggesting utility in both early diagnosis and prognostic stratification and its potential role as a pharmacodynamic marker responsive to interventions such as metformin and SGLT2 inhibitors is supported.

Yu Chen, Min Li, Min Yang et al. · 0 citations

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