Author

Yu-Bo Li

2 papers indexed here

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Open access Sep 2026

Saikosaponin A ameliorates acute lung injury by targeting eIF3f to regulate p62 ubiquitination and mitochondrial autophagy flux.

BACKGROUND Acute lung injury (ALI) is marked by an exaggerated inflammatory response, elevated oxidative stress, and impaired mitochondrial function, while effective targeted therapeutic strategies remain scarce. Saikosaponin A (SSA), a major active component of Bupleurum, exhibits anti-inflammatory activity, yet its d...

Cheng-Hao Bi, Ya-Wei Zhao, Jin-Xia Wei et al. · Phytomedicine · 0 citations

Review Open access Sep 2026

Nanomedicine design strategy for preferential elimination of cancer stem cells by targeted HIF-Warburg-immune evasion axis: Systematic review.

Cancer stem cells (CSCs) drive tumor recurrence, metastasis, and therapeutic resistance.Rather than exhibiting a uniform glycolytic phenotype, CSCs occupy tumor- and state-dependent metabolic configurations ranging from glycolysisdominant to oxidative phosphorylation（OXPHOS）-dependent and hybrid states. In hypoxic an...

Li-Li Song, Xiao-Xuan Wang, Dan-Dan Wu et al. · Pharmacological Research · 0 citations