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Yousra A. El-Maradny

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#protein folding Open access Oct 2026

New sulfonamide derivatives as HDAC inhibitors and apoptosis inducers: design, synthesis, in silico study and anticancer evaluation

The design and synthesis of new sulfonamide derivatives for potential histone deacetylase (HDAC) inhibition showed antiproliferative activity against three cancer cell lines, and this study suggests that compound 10 may serve as a lead molecule for further optimization toward new anticancer drugs.

Omkulthom M. Al Kamaly, Esamil M. El-Fakharany, Yousra A. El-Maradny et al. · 0 citations
Open access Oct 2026

Sustainable nanomedicine from olive leaf waste: biosynthesized ZnONPs with mechanistic validation against hepatocellular carcinoma

Agri-food waste is an underutilized source of valuable bioactive compounds. In this study, olive leaf pruning residues (Olea europaea L. cv. Soury) were used for the green synthesis of zinc oxide nanoparticles (OL-ZnONPs) as a natural reducing and stabilizing agent. Physicochemical characterization showed that the OL-Z...

Yasmin Mounir Mohamaden, S. El Hawary, E. El-Fakharany et al. · 0 citations

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