Jul 2026
Luteolin reverses chemoresistance in colorectal cancer cells via TET1/TDG-dependent epigenetic repression of β-catenin.
Resistance to 5-fluorouracil (5-FU) and oxaliplatin (OXT) remains a major cause of treatment failure in colorectal cancer (CRC). Luteolin, a dietary flavonoid with anticancer properties, has shown therapeutic potential in various malignancies, but its effects on chemotherapy-resistant CRC remain poorly understood. In t...
K. Kang, Mei-Jing Piao, H. Senavirathna et al.
· Food and Chemical Toxicology · 0 citations