Youichiro Wada

Hox/Meis-dependent gene-regulatory transition underlies cardiopharyngeal neural crest diversification

Neural crest cells (NCCs) are multipotent migratory cells essential for cardiac development, yet the lineage trajectories and gene regulatory networks underlying their differentiation in the cardiopharyngeal region remain unclear. Here, we integrate single-cell RNA-seq, spatial transcriptomics, and multiomic analyses t...