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Author

Yosuke Matsushita

2 papers indexed here

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Open access Oct 2026

Engineering T cell-engaging bispecific antibodies targeting KRAS G12V neoantigen across HLA-A*11:01 and HLA-A*03:01

Abstract Background T cells recognize tumor-specific neoantigens presented by human leukocyte antigen (HLA) molecules and can mediate potent antitumor immunity. However, most neoantigens are patient-specific, limiting their broad therapeutic applicability. KRAS G12V is a recurrent oncogenic mutation found in multiple c...

Xiao-Jing Wu, Clara Effenberger, Yosuke Matsushita et al. · 0 citations
Open access Sep 2026

Improved protocol for isolation and characterization of human thymic epithelial cells.

Thymic epithelial cells (TECs) play a vital role in the generation of immunocompetent and immunotolerant T cells. The understanding of TEC biology in model animals such as mice has advanced thanks to the cellular and molecular analyses of purified TEC populations, including cortical TECs (cTECs) and medullary TECs (mTE...

Naoko Matsui, H. Kondo, K. Maejima et al. · 0 citations

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