Cancer cell plasticity, the ability of tumor cells to switch between distinct cellular states, has emerged as a key mechanism driving tumor progression, metastasis and therapy resistance. Cancer cells exploit diverse plasticity mechanisms, including dedifferentiation, transdifferentiation, epithelial-mesenchymal transi...
Yoojeong Seo, Jin-Ho Jang, Jae-Il Park· Experimental and Molecular M...· 0 citations
Mucinous gastric adenocarcinoma (MGC) is a distinct histologic subtype characterized by poor prognosis and limited responsiveness to chemotherapy and immunotherapy. CRACD, an actin polymerization regulator, is frequently inactivated in gastric cancer (GC), with enrichment in mucinous subtypes. We found that genetic eng...
Yoojeong Seo, Jin-Ho Jang, Kyung-Pil Ko et al.· Nature Communications· 0 citations
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