Open access
Jul 2026
X-linked SYTL4 missense variant disrupts RAB27A-dependent vesicle trafficking and synaptic transmission in autism.
The findings implicate disrupted SYTL4-RAB27A-dependent vesicle trafficking in ASD pathogenesis and identify SYTL4 and RAB27A as previously unrecognized contributors to autism-associated synaptic deficits and behavior.
Yang Liao, Shuju Zhang, Xiaolei Zhang et al.
· Proceedings of the National... · 0 citations