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Yongjiang He

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Open access Aug 2026

Mendelian randomization and drug repurposing analysis identifies APOE as a potential therapeutic target for low back pain

Mendelian randomization identified Apolipoprotein E (APOE) as causally protective against LBP and pharmacological modulation of APOE via glucocorticoids, cytokine antagonists, or PPARγ agonists represents a novel strategy for early intervention in disc degeneration.

Jian-Ye Yang, Wei-Hui Qi, Dong Wang et al. · 0 citations

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