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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yongbo Liu

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Aug 2026

TRPM7 exacerbates testicular ischemia-reperfusion injury by activating the NLRP3 inflammasome to drive pyroptosis.

BACKGROUND Testicular ischemia-reperfusion injury (IRI) represents a critical determinant of fertility outcomes following torsion. Pyroptosis, an inflammatory form of cell death, involved in IRI within other organs, but its role and regulation in testicular damage remain unclear. The cation channel-kinase TRPM7 is a kn...

Xiao Wang, Xiaohong Yin, Yanze Li et al. · 0 citations

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