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Author

Yong Yu

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Sep 2026

Metabolic-epigenetic reprogramming of airway fibroblasts by K + N therapy suppresses IL-33 and ameliorates allergic asthma.

BACKGROUND Allergic asthma is a prevalent Th2-driven chronic inflammatory airway disease. While lung fibroblasts and fibroblast-derived IL-33 critically regulate airway inflammation, the fibroblast-specific role of IL-33 and the therapeutic mechanism of the immune regulatory small-molecule KQS1 and nicotinamide (K + N)...

Xiang-Dong Sun, Yuan-Yi Zhang, Ya-Dong Zheng et al. · 0 citations

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