Construction of a soluble mediator landscape and analysis of its clinical diagnostic potential in idiopathic pulmonary fibrosis.
BACKGROUND Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease. Current diagnosis primarily relies on imaging and histology, lacking sensitive and specific early biomarkers. Although soluble mediators play pivotal roles in IPF pathogenesis, their systematic characterization and clin...