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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Yong-Ping Li

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Review Open access Sep 2026

Hypoxia-Induced Gut-Brain Axis Remodeling and Insomnia: Mechanisms and Microbiota Adaptive Regulation from a Translational Perspective

Abstract High-altitude hypoxia frequently disrupts sleep–wake cycles, causing insomnia that impairs acclimatization, performance, and health. Emerging evidence implicates the gut–brain axis (GBA) in this disorder. Prolonged or severe hypoxia can disturb intestinal epithelial homeostasis through oxidative, inflammatory,...

Huaxiucairang Yang, Wen-Guang Lan, Jing Liu et al. · 0 citations

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