Author

Yong-Lun Luo

2 papers indexed here

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Open access

Lipid Nanoparticle-Mediated Delivery of CRISPR-Cas9 Components for Genome Editing.

Lipid nanoparticles (LNPs) are a clinically validated nonviral platform for the delivery of CRISPR-associated components. Composed of ionizable lipids, phospholipids, cholesterol, and PEG-lipids, LNPs enable the efficient encapsulation, protection, and cytosolic delivery of therapeutic cargo such as DNA, RNA, or protei...

A. Olsen, Camilla Blunk Brandt, Rasmus Karred Larsen et al. · Methods in molecular biology · 0 citations

#protein folding Open access Sep 2026

A comprehensive proteomic and transcriptomic mapping study found porcine and human kidneys exhibit a profoundly altered biological profile during warm ex vivo perfusion.

The molecular profile of donor kidneys is extensively remodeled during NMP, creating an ex vivo state that diverges considerably from in vivo physiology, challenging the use of in vivo biomarkers for ex vivo assessment.

V. Lantinga, Y. Zuo, C. Jaynes et al. · Kidney International · 0 citations