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Author

Yong-Jing Gao

2 papers indexed here

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Review Nov 2026

Neurotensin Signaling in Analgesia: Receptor Mechanisms, Targeted Drug Development, and Therapeutic Prospects for Pain and Comorbid Depression.

Opioids are effective for severe pain but are limited by adverse effects and the risk of opioid use disorder (OUD), while non-opioid analgesics may provide insufficient relief. Neurotensin (NT), an endogenous neuropeptide, has attracted interest as a potential analgesic, with encouraging findings mainly from preclinica...

Fei Xu, N. Sudhan, Ke Peng et al. · 0 citations
Open access Oct 2026

S-equol Mitigates Anxiety-like Behaviors Associated with Acute Hyperuricemia by Restoring Neuronal Excitability in the Medial Prefrontal Cortex.

Hyperuricemia (HUA) is a prevalent metabolic disorder closely linked to neuropsychiatric symptoms, including emotional disturbances. However, the neural mechanisms underlying this association remain largely unexplored. We established a mouse model of acute HUA by administering potassium oxonate (PO) and hypoxanthine (H...

Yue-Lian Sun, Xiao-Rui Duan, Yu-Xuan Shi et al. · 0 citations

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