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Author

Yong-Han He

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Review Open access Sep 2026

Senotherapeutic Potential of Anti-Diabetic Medications: Bridging Type 2 Diabetes and Accelerated Aging.

Aging and type 2 diabetes (T2D) are increasingly recognized as interconnected biological processes that share core pathogenic mechanisms, including cellular senescence, mitochondrial dysfunction, chronic low-grade inflammation, impaired autophagy, stem cell exhaustion, dysregulated nutrient sensing, and gut microbiota...

Hao-Ling Cui, A. Nisar, Zhong-Ping Duan et al. · 0 citations
Review Jul 2026

Complosome as a key modulator of cellular senescence, aging and age-related diseases.

This review synthesizes current research on how intracellular C3 (intC3), and intracellular C5 (intC5) in certain contexts engage in extensive crosstalk with the mTOR, NF-κB, and AMPK pathways to modulate core cellular processes to modulate age-related diseases.

Naheemat Modupeola Gold, M. N. Okeke, Samuel Ewhea Ajoronor et al. · 0 citations

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