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Author

Yong-Gui Gao

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Open access Aug 2026

MucD regulates alginate biosynthesis through the proteolytic control of AlgX and AlgK in Pseudomonas aeruginosa

It is demonstrated that MucD represses alginate biosynthesis post-translationally, in addition to its previously implicated role in transcriptional regulation, which defines a distinct activation mechanism and regulatory function for MucD and provides new insight into bacterial HtrA-like serine proteases.

Yu-Jun Jiang, Xin-Fu Yan, R. Ero et al. · 0 citations
Open access Sep 2026

Structure of the MurA-LpxC enzyme complex in modulating peptidoglycan and lipopolysaccharide biosynthesis.

Cryo-electron microscopy (cryo-EM) structures of the Pseudomonas aeruginosa MurA-LpxC complex in the absence and presence of the LpxC inhibitor CHIR-090 are determined, providing molecular insights into complex formation.

Joshua Yi Yeo, Xin-Fu Yan, Zhu Qiao et al. · 0 citations

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