Author

Yong-Chang Li

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Review Open access Oct 2026

Progress in pain mechanisms and management

Pain is a multifaceted sensory and emotional experience that profoundly affects human health and quality of life. It functions as a double-edged sword: while acute pain serves as a protective warning signal, chronic pain compromises physiological and psychological well-being. Pain is now widely regarded as the “fifth v...

Yong-Chang Li, Qian-Qian Chen, Fu-Yong Zhang et al. · Signal Transduction and Targ... · 0 citations

Open access Sep 2026

Upregulation of AK7 in ACC-VTA glutamatergic projections contributes to chronic inflammation pain in male mice.

Chronic inflammation pain is a complex pathological condition involving multiple mechanisms in both the peripheral and central nervous systems. Growing evidence indicates that an imbalance in central nervous system function plays a crucial role in the progression of chronic pain, yet the underlying neural circuits and...

Jie Huang, Meng-Ge Li, Ru-Yu Yan et al. · EMBO Reports · 0 citations