Author

Yong-Bin Wei

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Open access Oct 2026

Examinations of the heterogeneity in the structural brain connectome in schizophrenia

Abstract Background Schizophrenia (SCZ) is a heterogeneous disorder characterized by widespread brain dysconnectivity, yet it remains unclear whether variable structural dysconnectivity patterns reflect biologically and clinically meaningful subtypes. Methods We recruited 105 SCZ patients and 97 healthy controls, colle...

Shu Zhao, Qian-Hui Jin, Ze-Yao Wang et al. · Psychological Medicine · 0 citations

Open access Sep 2026

Beyond statistical thresholds: Mapping sequential ATN cascade transitions via brain structural topography in Alzheimer’s disease

Alzheimer’s disease is widely conceptualized as a biological continuum initiated by amyloid-β (Aβ) accumulation, followed by tau aggregation and neurodegeneration. Although the ATN framework is commonly used to define disease stages, its static biomarker categories may not fully capture the dynamic pathological transit...

Dong Wang, Shao-Zhen Yan, Rong-Shen Zhou et al. · Science Advances · 0 citations

Sep 2026

Prevalent and characteristic alterations in blood-brain transcriptomic-functional imaging coupling in schizophrenia.

Findings reveal distinct, reproducible dysregulation of peripheral-central functional coupling in SCZ, offering a multi-scale framework for understanding its pathophysiology and highlighting the potential of trans-scale features as candidate biomarkers for diagnosis and mechanistic insight.

Yu-Sha Ji, Yi-Feng Liu, Zhi-Qiang Mu et al. · Molecular Psychiatry · 0 citations