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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Y. Chandra

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3 papers indexed here

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Open access Sep 2026

Mitochondria-targeted esculetin mitigates age-associated cardiac remodeling through coordinated activation of AMPK-SIRT1 and inhibition of p38 MAPK signaling.

Age-associated cardiac remodeling, characterized by hypertrophy and fibrosis, is a major contributor to cardiovascular morbidity in the elderly and is often exacerbated by metabolic stressors such as hypercholesterolemia. Given the central role of mitochondrial dysfunction in these processes, we investigated whether mi...

Hridya Chempon, Sriravali Pulipaka, Altab Shaikh et al. · 0 citations
Sep 2026

Yohimbine attenuates bleomycin-induced skin fibrosis by modulating the PI3K/Akt-MAPK signaling: an integrated network pharmacology and in vivo study

It is demonstrated that yohimbine attenuates skin fibrosis by suppressing inflammatory and fibrotic responses, potentially through modulation of PI3K/Akt-MAPK signaling, and may represent a potential lead for further investigation in fibrotic skin disorders.

Abhisheik Eedara, J. S, Yogesh Chandra et al. · 0 citations
#diffusion models Sep 2026

SIGNAL-Nano: a sequentially gated red light-activable silicon-rhodamine nanoplatform for mitochondria-targeted theranostics.

A sequentially gated theranostic nanoplatform based on a silicon-rhodamine (Si-Rhod) photocage that integrates endogenous reactive oxygen species sensitivity with externally applied red light activation to achieve spatiotemporally programmable chemotherapy is reported.

Naga Mallika Reddy, Amar Singh, Soumyadeep Poddar et al. · 0 citations

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