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Author

Yizhi Jane Tao

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Review Oct 2026

Human astroviruses: molecular virology

SUMMARY Human astroviruses (HAstVs) are important etiologic agents of pediatric gastroenteritis and are increasingly recognized as pathogens associated with extraintestinal disease, including encephalitis and meningitis, particularly in immunocompromised individuals. Despite their clinical relevance, widespread prevale...

Adam Lentz, Tomás López, Matthew R. Ykema et al. · 0 citations
Open access Aug 2026

Identification of SKI-II as a host-protective immunomodulator against Staphylococcus aureus infection

This work identifies VCP as a druggable node for host-directed immunomodulation and highlights SKI-II as a prototype small molecule that boosts host tolerance to infection, thereby validating the C. elegans-based screening platform for discovering immunomodulators active in mammalian systems.

Li-Yang Zhang, Kai Ye, Charilaos Dellis et al. · 0 citations
Open access Aug 2026

Resolving Orsay Virus δ Protein Architecture Using Molecular Rulers in Single-Molecule Force Spectroscopy

This label-free method provides the first mechanical evidence of the δ protein’s multi-domain architecture, establishing a robust, multi-dimensional framework for decoding the mechanics of complex biomolecular assemblies in their native state.

Cynthia S. Deem, Sithara S. Wijeratne, Tsung-Cheng Lin et al. · 0 citations

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