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Yiwen Wang

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Review Open access Jul 2026

Research Progress of CRISPR-Cas Technology in the Treatment of Monogenic Diseases

This review systematically summarizes the developmental logic, core mechanisms, clinical applications, advantages and limitations of the three generations of CRISPR-Cas technology in monogenic disorders, and analyzes the key challenges such as delivery efficiency, long-term safety, and treatment accessibility.

Yiwen Wang · 0 citations