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Author

Yiwen Wang

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Open access Jul 2026

The single-cell atlas of programmed cell death signature: A machine learning-based prognostic framework in breast cancer.

A novel PCD-based prognostic signature for breast cancer is established and PDIA4 is identified as a functionally important oncogene, which effectively stratified patients into distinct risk groups and robustly predicted overall survival.

Ji-Xuan Jiang, Yiwen Wang, Yu-Ju Huang et al. · 0 citations
Review Open access Jul 2026

Research Progress of CRISPR-Cas Technology in the Treatment of Monogenic Diseases

This review systematically summarizes the developmental logic, core mechanisms, clinical applications, advantages and limitations of the three generations of CRISPR-Cas technology in monogenic disorders, and analyzes the key challenges such as delivery efficiency, long-term safety, and treatment accessibility.

Yiwen Wang · 0 citations

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