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Open access Oct 2026

Comparative evaluation of metagenomic and targeted next-generation sequencing for pathogen detection in bronchoalveolar lavage fluid from patients with lower respiratory tract infections: a retrospective cohort study

Both tNGS and mNGS offer substantial diagnostic value for LRTIs, with tNGS showing particular utility in identifying fastidious and low-titer pathogens and both platforms demonstrated diagnostic efficacy superior to traditional laboratory tests.

Rui Zhao, He-Ya Na, Wei Miao et al. · 0 citations

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