Author

Ying Zhang

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Open access Jul 2026

Isoalantolactone inhibits pancreatic ductal adenocarcinoma progression via direct targeting of NLRP3-mediated inflammation-angiogenesis axis

IATL functions as a novel NLRP3 pathway inhibitor, suppressing angiogenesis through anti-inflammatory mechanisms, thereby effectively inhibiting PDAC progression and suggesting that IATL holds potential as a therapeutic agent for pancreatic cancer.

Ying Zhang, Changquan Liu, Shengjiang Liu et al. · Frontiers in Pharmacology · 0 citations