Aptamer-functionalized terahertz metasensor for sensitive and specific determination of alpha-fetoprotein.
Alpha-fetoprotein (AFP) is a key serum biomarker for the early diagnosis of hepatocellular carcinoma (HCC). In this study, a dual-band terahertz (THz) metasurface sensor (metasensor) was developed and functionalized with computationally selected aptamers for sensitive and specific detection of AFP. A 1000-sequence ssDN...