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Review Open access Sep 2026

Association of Elevated Lipoprotein(a) levels with vulnerable plaque features assessed by multimodality coronary imaging in patients with coronary artery disease: A systematic review and Meta-analysis

This meta-analysis suggests that high Lp(a) levels are associated with several imaging-defined high-risk coronary plaque features, with the most robust evidence observed for OCT-derived TCFA and plaque rupture.

Jia-Yu Zhang, Yang Tang, Yu-Yang Cao et al. · 0 citations
Open access Oct 2026

Combined Effects of Biomarkers in NLRP3 Inflammasome Axis and Cardiovascular Outcomes in Multivessels Disease

Background Inflammation plays a crucial role in adverse outcomes of coronary artery disease. NOD-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome activates 2 classical pathways: interleukin-1β (IL-1β)/IL-6/high-sensitivity C-reactive protein (hsCRP) and IL-18/IL-6/hsCRP. However, the predicti...

Jia-Wen Li, Xiao-Zeng Wang, Zhen-Yu Liu et al. · 1 citation
Aug 2026

Combined triglyceride-glucose index and systemic inflammation for long-term risk stratification in major adverse cardiovascular events: a 10-year prospective study.

BACKGROUND AND AIMS Insulin resistance and systemic inflammation are key drivers of atherosclerosis but are typically evaluated separately. This study aimed to determine whether integrating the triglyceride-glucose (TyG) index with inflammatory markers improves long-term risk stratification for major adverse cardiovasc...

Zhao Ma, P. Zhu, Jing-Jing Xu et al. · 0 citations

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