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Review Open access Sep 2026

Aptamer-based technologies for extracellular vesicle analysis and engineering: from isolation to functional applications

Recent progress in integrating aptamers into EV research is highlighted across three interconnected domains: the selection of aptamers against EV-associated surface markers; the development of aptamer-based methods for EV capture and isolation; and the use of aptamer-functionalized EVs for targeted drug delivery and im...

Xue-Fei Li, You-Yu Zhang, Dan-Ping Zhang et al. · 0 citations
Review Open access Sep 2026

Aptamer-based technologies for extracellular vesicle analysis and engineering: from isolation to functional applications

Extracellular vesicles (EVs) are natural mediators of intercellular communication and hold promise for disease diagnosis and drug delivery, yet their intrinsic heterogeneity complicates isolation, molecular profiling, and targeted delivery. Aptamers, owing to their high affinity, specificity, chemical tunability, and s...

Xue-Fei Li, You-Yu Zhang, Dan-Ping Zhang et al. · 0 citations

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