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Oct 2026

3-Indoleacetonitrile inhibits Singapore grouper iridovirus via dual mechanisms: direct interference with viral life cycle and activation of IRF3-mediated type I interferon response.

Findings demonstrate that 3-indoleacetonitrile inhibits SGIV infection through both direct antiviral action and activation of the IRF3-mediated type I IFN pathway, suggesting its potential as a natural candidate for the prevention and control of grouper iridovirus disease.

Chen-Ao Li, Ming-Zhu Liu, Qing Yu et al. · 0 citations

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