KLF2 regulates CD8 T cell differentiation and migration in infection and cancer 2254075
Besides acute infection, CX3CR1+ effector-like CD8 T cells also appear in chronic infection and cancer. Whether there is a central transcriptional regulator of the effector fate is unclear. Here, using joint single-cell profiling of the transcriptome and epigenome of chimeric antigen receptor (CAR) T cells...