Author

Yingjun Zhang

h-index 1 View on Semantic Scholar

We have 3 of 9 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Oct 2026

Studies on the convenient synthesis, fluorescence properties and bioactivity of chromenonitriles.

The synthesis of chromenonitriles remains largely underexplored, primarily due to the limited availability of suitable substrates and the generally unsatisfactory yields of existing methods. Herein, we report a new method that enables the efficient construction of chromenonitriles under mild, metal-free conditions, usi...

Sheng-Yu Li, Zhong-Hao Li, Chu-Ming Pang et al. · Organic and biomolecular che... · 0 citations

Aug 2026

Class I capsid assembly modulators induce potent anti-HBV activity through direct viral suppression, innate immune activation and caspase-3-independent clearance of infected hepatocytes.

Capsid assembly modulators (CAMs) are promising antiviral agents for chronic hepatitis B virus (HBV) infection. This study investigates the anti-HBV activity and immunomodulatory effects of Class I CAMs (CAM-A) in vitro and in vivo. In HepAD38 cells, CAM-A treatment significantly upregulated the expression of interfero...

Pu-Shuo Wang, Xin-Chang Liu, Yong Xie et al. · Antiviral Research · 0 citations

Jul 2026

Design, synthesis and evaluation of benzo[4,5]thiazolo[3,2-a]pyrimidin-4-one derivatives as novel MTA cooperative PRMT5 inhibitors for the treatment of MTAP-deleted cancers.

Compound 9u exhibited significant antiproliferative activity in MTAP-deleted HCT116 cancer cells, with an IC50 value of 13 nM, exhibiting 70-fold selectivity over MTAP wild type HCT116 cells, and 9u displayed robust efficacy across diverse MTAP-deleted cancer cell lines, achieving IC50 values of <1.5-51 nM.

Bing Liu, Shao-Yan Li, Hui Shi et al. · Bioorganic chemistry (Print) · 0 citations