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Ying-Hong Cui

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Open access Aug 2026

Activation of G12-type G proteins in pancreatic β cells protects against impaired glucose homeostasis

Impaired insulin secretion represents a key feature of type 2 diabetes (T2D), a major global health burden. Insulin release from pancreatic β cells is regulated by G protein–coupled receptors linked to different functional classes of G proteins. The potential metabolic role of β cell G12/13 (G12 hereafter) signaling re...

Srinivas Pittala, Liu Liu, Dhanush Haspula et al. · 0 citations

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