Gene signatures of palmitoylation and fatty acid metabolism predict prognosis and immunotherapy response in breast cancer patients by machine learning, single-cell analysis, and experimental validation
Background Palmitoylation and dysregulated fatty acid metabolism are key components of tumor metabolic reprogramming and play important roles in the initiation, progression, and immune regulation of breast cancer (BRCA). However, their systemic molecular characteristics and clinical predictive value remain incompletely...