Author

Yinbo Wang

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Open access Aug 2026

Pocket-PROTACs: an interpretable pocket-aware deep learning framework for predicting PROTAC-induced protein degradation

Pocket-PROTACs is proposed, a pocket-aware attention-based framework for predicting PROTAC-induced protein degradation from a triplet of POI, E3 ligase, and PROTAC, which consistently outperforms fingerprint-based baselines and recent deep learning methods.

Kai Chen, Zhijian Huang, Yinbo Wang et al. · Bioinformatics · 0 citations