YIN Jie, WANG Xue, DENG Shukai

Effects of disulfiram on proliferation, apoptosis and gefitinib resistance of lung cancer cell line H1975

Objective To investigate the effects of disulfiram (DSF) on the proliferation, apoptosis and gefitinib sensitivity of non-small cell lung cancer H1975 cells. Methods H1975 cells were cultured in vitro and treated with different concentrations of disulfiram for 24, 48, and 72 hours. The CCK-8 assay was used to assess th...