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Performing deliberate mathematical reasoning in visual contexts is a hallmark of advanced Multimodal Large Language Models (MLLMs) and requires a sophisticated synthesis of perceptual grounding and symbolic logic. However, in the realm of mathematical functions, our investigation reveals a critical modality interferenc...
This paper introduces Caduceus, a family of MoE-enhanced foundation models built with a hierarchical pre-training paradigm to jointly integrate biological and natural language, and incorporates a multi-task instruction tuning phase, enabling robust protein parsing and natural language question answering.
IgGM2 follows a structure-to-design strategy: it first learns how immune receptors are positioned around fixed target structures, and then transfers this target-conditioned structural prior to CDR design, allowing frame-work geometry to adapt to designed CDRs without separate inverse folding or external sidechain packi...
HiCLR is the first foundation model that can be broadly applied to various synthesis-related tasks, and it achieves state-of-the-art performance in reaction classification, reaction condition recommendation, reaction yield prediction, synthesis planning, and even molecular property prediction.
This paper introduces Caduceus, a family of MoE-enhanced foundation models built with a hierarchical pre-training paradigm to jointly integrate biological and natural language, and incorporates a multi-task instruction tuning phase, enabling robust protein parsing and natural language question answering.
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