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Author

Yige Chen

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Aug 2026

Methylnissolin preserves chondrocyte homeostasis and attenuates experimental osteoarthritis through modulation of the PI3K-AKT-NF-κB signaling axis.

BACKGROUND Osteoarthritis (OA) involves extracellular matrix (ECM) degradation, inflammation, oxidative stress, mitochondrial dysfunction, and chondrocyte loss. Methylnissolin (MN) is a natural isoflavonoid with anti-inflammatory and antioxidant properties, but its effects in OA remain unclear. PURPOSE To evaluate th...

Xiuzhi Zhang, Chaochao Gong, Jia-Le Zhou et al. · 0 citations

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