Responsible Integration of AI in Cancer Genomics: Barriers, Risks, and Pathways to Trustworthy Clinical Translation
A conceptual framework and roadmap for addressing four interrelated translational failure domains through rigorous validation, uncertainty-aware methods, interoperable infrastructures, regulatory alignment, and human oversight across the AI lifecycle is proposed.
B. Ilgen, Yiannos S. Tolias, Denise Kühnert et al.
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