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Yian Ling

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Open access Sep 2026

Celecoxib Ameliorates Chronic Restraint Stress-Induced Depression-Like Behavior in Sprague-Dawley Rats

Introduction Chronic stress is associated with depressive-like behaviors, dysregulation of the hypothalamic-pituitary-adrenal axis, and changes in inflammatory signaling. Celecoxib is a selective cyclooxygenase-2 inhibitor that has been investigated as a potential adjunctive treatment for depression; however, its effec...

Yian Ling, Jing Li, Wan-Bin Liu et al. · 0 citations
Review Open access Sep 2026

β-hydroxybutyrate in depression: Neuropharmacological mechanisms and therapeutic potential.

The biosynthesis and transport of BHB is synthesized, the evidence linking BHB to depression across animal and human studies is critically evaluated, and the relative strength of the proposed neuropharmacological mechanisms are appraised.

Wan-Bin Liu, Xiu-Qing Cao, Yian Ling et al. · 0 citations

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