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Author

Yi-Yang Ding

2 papers indexed here

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Open access Oct 2026

Distinct cellular dynamics following CD19 and CD7 CAR-T therapies revealed by high-dimensional CyTOF analysis and impact on clinical outcomes

Compared with CD19 CAR-T therapy, CD7 CAR-T therapy was characterized by reduced CD8+ CAR-T persistence, early exhaustion, and delayed immune reconstitution, correlating with increased infections and higher non-relapse mortality.

Zhi-Peng Zhou, Yi-Yang Ding, Zhuo-Jun Liu et al. · 0 citations
Sep 2026

NK3 subsets are linked to NK cell exhaustion and immunotherapy responsiveness in tumor.

Natural killer (NK) cells constitute the first line of human immune defense. They have attracted extensive research in the field of tumor immunity owing to their potent cytotoxicity, robust cytokine secretion, and immunomodulatory capacity. However, chronic tumor antigen exposure would induce exhaustion in NK cells (NK...

Zi-Xuan Gou, Yu-Tong Bao, Li-Hong Liu et al. · 0 citations

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