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Sep 2026

Programming 2,3-butanediol biosynthesis in Saccharomyces cerevisiae with AI-optimized dual-optogenetic switches.

Microbial cell factories promise sustainable biomanufacturing, yet balancing cellular growth and product synthesis remains a fundamental productivity bottleneck. While traditional static metabolic engineering fails to precisely orchestrate metabolic flux across temporal and spatial dimensions, optogenetic approaches of...

Sai-Nan Yang, Ren-Mei Liu, De-Chong Ou et al. · 0 citations
Open access Sep 2026

Mitotic assembly of respiratory supercomplexes ensures accurate cell division and fuels tumor growth.

Proteomic analysis of BN-PAGE fractions shows that assembly of the mitochondrial respiratory supercomplexes is markedly enhanced during mitosis in HeLa and MDA-MB-468 cancer cells, and reveals supercomplex assembly as a key mechanism coordinating mitochondrial fission with metabolic adaptation to support cell division...

Ting Wang, Ao-Xing Cheng, Ling-Yu Kong et al. · 0 citations

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