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Author

Yi-Yan Lin

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Open access Oct 2026

Intestinal 3-methylindole exacerbates sepsis-induced neuroinflammation through microglial NLRP3 inflammasome activation

A specific gut microbial pathway is identified and sepsis-induced expansion of Escherichia coli and its overproduction of the metabolite 3-methylindole are key aggravating factors, which contributes to a new mechanistic understanding of SAE pathogenesis.

Heng Fang, Si-Min Wu, Pei-Xian Huang et al. · 0 citations

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