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Yi-Xun Lu

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Open access Sep 2026

Pyrroloquinoline Quinone Attenuates Traumatic Brain Injury‐Induced Secondary Damage by Activating PINK1/Parkin‐Mediated Mitophagy and Suppressing ASS1/CPS1‐Driven Arginine Biosynthesis

PQQ attenuates secondary injury after TBI in male mice, in association with increased markers of PINK1/Parkin‐mediated mitophagy initiation and suppressed ASS1/CPS1‐driven arginine biosynthesis, identifying a candidate dual‐axis mechanism and nominating the mitophagy‐arginine axis as a target for neuroprotection in TBI...

Ya-Nan He, Lu-Fei Yu, Yi-Xun Lu et al. · 0 citations

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