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Author

Yi-Wen Zhang

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Review Oct 2026

From functional complexity to structural modification: A systematic review of the ongoing development of targeted PXR drugs.

The pregnane X receptor (PXR, NR1I2) is a ligand-activated nuclear receptor that regulates xenobiotic and endobiotic metabolism and has been associated with diverse physiological and pathological processes. However, the biological consequences of PXR modulation are highly context-dependent, and the translational releva...

Meng-Yao Wang, Wu-Yi Wu, Guo-Nian Zhu et al. · 0 citations

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