Open access
Aug 2026
DACH1 SUMOylation protects against diabetic cardiomyopathy by suppressing endoplasmic reticulum stress.
INTRODUCTION Endoplasmic reticulum (ER) stress is a key driver of diabetic cardiomyopathy (DCM), but its upstream regulators are incompletely defined. The transcription factor DACH1 is genetically linked to diabetes and cardiovascular risk, yet its role in the diabetic heart is unknown. OBJECTIVES This study aimed to...
Jie Lin, Na Liu, Bo Li et al.
· Journal of Advanced Research · 0 citations