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Author

Yi Tang

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Oct 2026

Hydrogel compartmentalization enables flow cytometric selection of engineered yeast producing complex natural products.

Saccharomyces cerevisiae is a powerful chassis for biosynthesis of plant-derived natural products, but optimizing multi-enzyme pathways remains bottlenecked by the lack of scalable screens for small molecules with weak to no fluorescence. Here we present a colony-level, fluorescence-activated cell sorting (FACS) workfl...

Moriel J. Dror, Cayden Williamson, Yi Tang et al. · 0 citations
Jul 2026

Genome Mining of the Biocontrol Fungus Trichoderma afroharzianum T22 Led to the Discovery of Dehydrobutyrine-Containing Lipopeptides.

Elucidating natural products encoded by cryptic biosynthetic gene clusters (BGCs) in agriculturally important biocontrol fungi such as Trichoderma afroharzianum T22 (ThT22) could lead to the discovery of new compounds that may be explored as potential agrochemicals. Herein, we discovered new lipopeptide natural product...

Zuo-Dong Sun, Brandon Wong, Sydney Choi et al. · 0 citations

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