Complementary enhancement of osmotic tolerance in Ligilactobacillus salivarius AR612 by exogenous purine nucleobases and gene engineering.
High-density fermentation and high-sugar environments place substantial osmotic stress on the probiotic strain Ligilactobacillus salivarius, causing its viability to be insufficient for food industrial applications, biological preservation, and probiotic formulation development. We investigated the efficacy of exogenou...