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Yi Shen

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Open access Sep 2026

γ-Glutamylcysteine alleviates hypertension and vascular remodeling in SHR by suppressing oxidative stress through Keap1 S-glutathionylation

Abstract Objectives Pathological arterial remodeling heavily depends on the aberrant proliferation and migration of vascular smooth muscle cells (VSMCs). This study explores how γ-Glutamylcysteine (γ-GC) regulates VSMC signaling to mitigate hypertensive structural damage. Methods Spontaneously hypertensive rats (SHR) a...

Jian-Zhen Lei, Yue-Ru Kong, Chao Ye et al. · 0 citations

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